Daianna Gonzalez-Padilla

About me

I’m a post-baccalaureate researcher analyzing omics data to study brain function and disease, and drug response. My main interest is the development of algorithms to analyze biological data and their application to answer a wide range of biomedical questions.

Education

📍: on-site | : remote

National Autonomous University of Mexico (UNAM), Morelos, Mexico	2020 - 2024
B.S. in Genomic Sciences (LCG)	📍🇲🇽

Tecnologico de Monterrey (ITESM), Zacatecas, Mexico	2017 - 2020
High School	📍🇲🇽

Research experience

Sanger Institute, Cambridge, UK	Sept 2024 - Present
Research assistant in the Immune Genomics group of Dr. Gosia Trynka.	📍🇬🇧

Lieber Institute for Brain Development (LIBD), Baltimore, MD	Jun 2022 - Jun 2024
Undergraduate researcher in the Data Science team of Dr. Leonardo Collado-Torres.	📍🇺🇸 \|

Karolinska Institutet (KI), Stockholm, Sweden	Aug - Nov 2023
Undergraduate researcher in the Personalized Medicine and Drug Development lab of Dr. Volker Lauschke.	📍🇸🇪

Brigham and Women’s Hospital (BWH), Boston, MA	Feb - Jul 2022
Intern in the Genomics and Bioinformatics Hub with Dr. Xianjun Dong.

Center for Genomic Sciences (CCG), Morelos, Mexico	Feb - Jul 2021
Undergraduate researcher in the Systems Biology lab of Dr. Julio A. Freyre-Gonzalez.	📍🇲🇽 \|

Publications

Population-scale variability of the human UDP-glycosyltransferase gene family. | Gonzalez-Padilla, D., Camara, M. D., Lauschke, V. M., & Zhou, Y. (2024).

Molecular impact of nicotine and smoking exposure on the developing and adult mouse brain. | Gonzalez-Padilla, D., Eagles, N. J., Cano, M., Pertea, G., Jaffe, A. E., …, Martinowich, K., & Collado-Torres, L. (2024).

Benchmark of cellular deconvolution methods using a multi-assay reference dataset from postmortem human prefrontal cortex. | Huuki-Myers, L. A., Montgomery, K. D., Kwon, S. H., Cinquemani, S., Eagles, N. J., Gonzalez-Padilla, D., …, Collado-Torres, L. (2024).

Presentations

Annual Bioconductor Conference 2023 , Boston, MA	Aug 2023
Presented a short talk titled “Modeling the effects of nicotine and smoking exposures on the developing mouse brain”.	📍🇺🇸
Presented a long workshop titled “A Bioconductor-style differential expression analysis powered by SPEAQeasy”.
Presented a Birds-of-a-feather session titled “Bioconductor and the Latin American Bioinformatics Landscape”.

NIDA Genetics and Epigenetics Meeting 2024, Bethesda, MD	Jun 2024
Poster presentation titled “Transcriptomic changes in habenula and amygdala following chronic fentanyl self-administration in rats” \| Yalcinbas, E. & Gonzalez-Padilla, D.	📍🇺🇸

PGRN Annual Meeting 2024, Columbus, OH	Sept 2024
Oral presentation titled “Population-Scale Variability in the Human Uridine Diphosphate (UDP)-Glycosyltransferase Gene Family”.	📍🇺🇸

Software

smokingMouse to provide access to bulk RNA-seq data sets from Gonzalez-Padilla et al. (2024).

Tutorials and teaching materials

SPEAQeasy Bioconductor Workshop 2023 to demonstrate how to utilize the outputs of the RNA-seq processing pipeline SPEAQeasy in downstream processing and differential gene expression analysis.
CSHL Statistical Analysis of Genome Scale Data course 2023 to teach bulk RNA-seq data processing and exploratory analyses in the CSHL course of 2023.
CSHL Statistical Analysis of Genome Scale Data course 2024 to teach differential gene expression with limma-voom and the basics of spatial transcriptomics in the CSHL course of 2024.

Skills

Programming: , , , C/C++, and Perl.
Bioconductor package development
GitHub
Compute clusters and Bash scripting
Quarto websites 🌐

Achievements

National CARMA Women’s Mathematics Olympiad	Mar 2020
🥇 Gold medal	📍🇲🇽

33rd National Mexican Mathematics Olympiad (OMM)	Nov 2019
🗞 Honorable mention	📍🇲🇽

Interests and Hobbies

I love to paint 🎨 practice yoga 🧘🏻‍♀ cheese 🧀 and dogs 🐩.

Please refer to my CV for more details about my education, past research and teaching experience, presentations and courses, publications and ongoing projects. In case of questions or queries, feel free to contact me in any of my social media.

Last Updated: 2024-11-07